Dendritic cell-targeted vaccines — hope or hype?

Dendritic Cell-Targeted Vaccines

Despite significant effort, the development of effective vaccines inducing strong and durable T-cell responses against intracellular pathogens and cancer cells has remained a challenge. The initiation of effector CD8(+) T-cell responses requires the presentation of peptides derived from internalized antigen on class I major histocompatibility complex molecules by dendritic cells (DCs) in a proc...

Stem cell therapy: hope or hype?

service Email alerting box at the top left of the article Receive free email alerts when new articles cite this article-sign up in the Topic collections (558 articles) Haematology (including blood transfusion) (537 articles) Basic sciences (361 articles) Reproductive medicine Articles on similar topics can be found in the following collections Notes To order reprints follow the "Request Permiss...

Pharmacogenomics: Hope or Hype?

Much has been made of the potential for personalnot altruistic companies. Incyte Inc. alone holds US ised medicine, where a genomic screen of a patient patents on more than 350 genes and has an estimated could determine which drugs will work and be free of 6,500 applications pending with 10 more applied for side effects in an individual. Much of the hope based each week [3]. They hope to make p...

Genital herpes: hype or hope?

NEUROIS : HYPE OR HOPE ? Panels